VOLUME 9 , ISSUE 1--3 ( January-December, 2024 ) > List of Articles
Krutika J Mundra, Anubhuti Sharma, Sukriti Singh, Geetika Chopra, Manju Bhaskar
Keywords : Bipolar disorder, Case report, Grave's disease, Mania, Psychosis
Citation Information : Mundra KJ, Sharma A, Singh S, Chopra G, Bhaskar M. A Case Report Unveiling the Convergence of Mania and Hyperthyroidism in a Young Man: A Symphony of Discordance. J Mahatma Gandhi Univ Med Sci Tech 2024; 9 (1--3):1-4.
DOI: 10.5005/jp-journals-10057-0238
License: CC BY-NC 4.0
Published Online: 23-10-2024
Copyright Statement: Copyright © 2024; The Author(s).
Aim: This case report delves into the intricate relationship between bipolar affective disorder (BD) and hyperthyroidism, presenting the case of a 28-year-old male experiencing a manic episode with psychotic features secondary to an unmanaged thyroid condition. Case description: A 28-year-old male presented with a 1-month history of hyperphagia, weight loss, diaphoresis, tremors, insomnia, hyperactivity, grandiosity. Past history revealed a similar episode resolving spontaneously. Mental status examination displayed elevated mood, labile affect, and delusions. Further investigations revealed hyperthyroidism. Initial management included antipsychotics, mood stabilizers, and a beta blocker. Conclusion: In conclusion, this case highlights the complex intertwining of hyperthyroidism and mania. While hyperthyroidism can mimic or exacerbate underlying bipolar disorder, the exact mechanisms remain under investigation. Studies suggest involvement of catecholamines, neurotransmitters, and inflammation. This case underscores the potential for hyperthyroidism to act as a trigger, particularly in individuals with a predisposition to mood disorders. Clinical significance: Psychosis is uncommon in Graves’ disease, despite its frequent symptoms like agitation and mood swings. A thyroid function test becomes crucial for individuals experiencing these or other psychiatric symptoms, such as delirium, to rule out underlying medical causes during initial screening. Likewise, when encountering new or recurring mental health conditions, inquiring about potential hypothyroidism or hyperthyroidism symptoms from both patients and caregivers is valuable.