Citation Information :
Sharma V, Dhaliwal H, Yadav S. Primary Intraosseous Carcinoma Arising in a Mandibular Keratocystic Odontogenic Tumor: A Case Report. J Mahatma Gandhi Univ Med Sci Tech 2020; 5 (3):96-99.
Primary intraosseous carcinoma (PIOC) is a rare squamous cell carcinoma (SCC) arising within the jaw, which has no initial connection with the oral mucosa, overlying skin, antral or nasal mucosa. Primary intraosseous carcinoma is also designated as odontogenic carcinoma because it is considered to develop from the epithelium involved in odontogenesis. It is considered a rare lesion, but may not be as rare as commonly believed. It may arise de novo or as a consequence of malignant transformation of a benign cyst or tumor. It is locally aggressive with a poor prognosis. A case of primary intraosseous SCC of the mandible, with evidence of origin in an odontogenic cyst, is presented.
Grisar K, Schol M, Hauben E, et al. Primary intraosseous squamous cell carcinoma of the mandible arising from an infected odontogenic cyst: a case report and review of the literature. Oncol Lett 2016;12(6):5327–5331. DOI: 10.3892/ol.2016.5378.
Anneroth G, Hansen LS. Variations in keratinizing odontogenic cysts and tumors. Oral Surg Oral Med Oral Pathol 1982;54(5):530–546. DOI: 10.1016/0030-4220(82)90192-X.
Pindborg JJ, Kramer IR, Torloni H eds. Histological typing of odontogenic tumors, jaw cysts, and allied lesions. International Histological Classification of Tumors. Geneva, Switzerland: World Health Organization;1971.
To EHW, Brown JS, Ward-Booth RP, et al. Primary intraosseous carcinoma of the jaws. Three new cases and review of the literature. Br J Oral Maxillofac Surg 1991;29(1):19–25. DOI: 10.1016/0266-4356(91)90168-5.
Thomas G, Pandey M, Mathew A, et al. Primary intraosseous carcinoma of the jaw: pooled analysis of world literature and report of two new cases. Int J Oral Maxillofac Surg 2001;30(4):349–355. DOI: 10.1054/ijom.2001.0069.
Huang JW, Luo HY, Li Q, et al. Primary intraosseous squamous cell carcinoma of the jaws. Archi Pathol Laborat Med 2009;133(11):1834–1840.
Kaffe I, Ardekian L, Peled M, et al. Radiological feature of primary intraosseous carcinoma of the jaws: analysis of the literature and report of a new case. Dentomaxillofac Radiol 1998;27(4):209–214. DOI: 10.1038/sj.dmfr.4600351.
Eversole LR, Sabes WR, Rovin S. Aggressive growth and neoplastic potential of odontogenic cysts. Cancer 1975;35(1):270–282. DOI: 10.1002/1097-0142(197501)35:1<270::AID-CNCR2820350134>3.0.CO;2-Y.
Cawson RA, Binnie WH, Speight PM, et al. Luca's pathology of tumors the oral tissues. London: Chur-chill Livingstone; 1998. pp. 36–76.
Suei Y, Tanimoto K, Taguchi A, et al. Primary intraosseous carcinoma: review of the literature and diagnostic criteria. J Oral Maxillofac Surg 1994;52(6):580–583. DOI: 10.1016/0278-2391(94)90094-9.