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VOLUME 3 , ISSUE 3 ( September-December, 2018 ) > List of Articles


Carbamazepine-induced Pancytopenia: A Rare Entity

Pankaj Mathur, Kishore Moolrajani, Vishal Mishra, Ankit Jain

Keywords : Carbamazepine, Pancytopenia

Citation Information : Mathur P, Moolrajani K, Mishra V, Jain A. Carbamazepine-induced Pancytopenia: A Rare Entity. J Mahatma Gandhi Univ Med Sci Tech 2018; 3 (3):97-98.

DOI: 10.5005/jp-journals-10057-0082

License: CC BY-NC 4.0

Published Online: 27-09-2019

Copyright Statement:  Copyright © 2018; The Author(s).


Carbamazepine is an anticonvulsant medication used primarily in the treatment of epilepsy, seizure disorder, neuropathic pain, some psychiatric disorders such as schizophrenia, and as a second-line agent in bipolar disorders. Generally, it is safe to use with some nonserious side effects. However, a clinician has to be alert regarding some of its uncommon but serious side effects. Here we discuss a rare case who developed carbamazepine-induced pancytopenia. The offending drug was stopped and pancytopenia recovered within a few days.

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  1. Brunton L, Chabner B, Knollmann B. The pharmacological basis of therapeutics. 12th ed., McGraw Hill, Goodman and Gilman's; 2011. p. 594.
  2. Satoskar RS, Rege N, Bhandarkar SD. Pharmacology and pharmacotherapeutics, 24th ed., India: Elsevier; 2015. p. 136.
  3. Aster RH, Curtis BR, McFarland JG, et al. Drug-induced immune thrombocytopenia: pathogenesis, diagnosis and management. J Thromb Haemost 2009;7(6):911–918. DOI: 10.1111/j.1538-7836.2009.03360.x.
  4. Shigeyama Y, Hishida H, Doi T, et al. A case of marked thrombocytopenia during administration of carbamazepine. J Jpn Soc Clin Anesth 2005;25(2):162–165. DOI: 10.2199/jjsca.25.162.
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