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VOLUME 3 , ISSUE 2 ( May-August, 2018 ) > List of Articles


Dengue Fever: A Sight-threatening Ailment

Sandeep Shivran, Daya C Gupta

Keywords : Dengue fever, Macular edema, Ocular manifestations, Optic neuritis

Citation Information : Shivran S, Gupta DC. Dengue Fever: A Sight-threatening Ailment. J Mahatma Gandhi Univ Med Sci Tech 2018; 3 (2):63-65.

DOI: 10.5005/jp-journals-10057-0077

License: CC BY-NC 4.0

Published Online: 01-08-2016

Copyright Statement:  Copyright © 2018; The Author(s).


Introduction: Dengue fever, a mosquito-borne viral disease endemic in tropical and subtropical areas. In humans, it is transmitted by the infected female Aedes aegypti mosquito. In dengue fever, the symptoms range from flu-like symptoms to lethal complications, along with ocular manifestations and other positive laboratory findings. Objective: The aim of this study was to evaluate the ophthalmic manifestations allied with the dengue fever. Materials and methods: The study was carried out in 150 indoor patients diagnosed with dengue fever. All indoor patients underwent complete systemic and ophthalmic examination in Department of Ophthalmology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India. Results: A total of 150 patients were diagnosed with dengue fever, of which 95 (63.3%) were men and 55 (36.7%) were women. The study group ranges between 20 years and 60 years. Of the 150 patients, only 88 patients (58.7%) were having ocular manifestations. Subconjunctival hemorrhage is noted in 68 patients (45.3%). Anterior uveitis in 5 (3.3%) patients, panuveitis in 1 (0.7%) patient, retinal hemorrhages in 12 (8%) patients, macular edema in 1 (0.7%) patient, and bilateral optic neuritis in 1 (0.7%) patient. Ocular manifestations resolved in all the cases that came for followup except one case of bilateral optic neuritis. Platelet count improvement also attributed for the same. Conclusion: The inference is that the clinicians should have a heightened awareness of dengue-related ophthalmic complications and should facilitate a prompt referral for ophthalmic assessment and management, so that with early interventions, we can restore the vision.

  1. World Health Organization. Dengue and Severe Dengue.
  2. Yip VC, Sanjay S, Koh YT. Ophthalmic complications of dengue fever: a systematic Review. Ophthalmol Ther 2012;1(1):2. DOI: 10.1007/s40123-012-0002-z.
  3. Hussain I, Afzal F, Shabbir A, et al. Ophthalmic manifestation of dengue fever. Ophthalmol Update 2012;10:93–96.
  4. Nainiwal S, Garg SP, Prakash G, et al. Bilateral vitreous haemorrhage associated with dengue fever. Eye (Lond) 2005;19:1012–1013. DOI: 10.1038/sj.eye.6701704.
  5. Cruz-Villegas V, Berrocal AM, Davis JL. Bilateral choroidal effusions associated with dengue fever. Retina 2003;23:576–578. DOI: 10.1097/00006982-200308000-00031.
  6. Chlebicki MP, Ang B, Barkham T, et al. Retinal haemorrhages in 4 patients with dengue fever. Emerg Infect Dis 2005;11:770–772. DOI: 10.3201/eid1105.040992.
  7. Siqueira RC, Vitral NP, Campos WR, et al. Ocular manifestations in dengue fever. Ocul Immunol Inflamm 2004;12:323–327. DOI: 10.1080/092739490500345.
  8. Lim WK, Mathur R, Koh A, et al. Ocular manifestations of dengue fever. Ophthalmology 2004;111:2057–2064. DOI: 10.1016/j.ophtha.2004.03.038.
  9. Wen KH, Sheu MM, Chung CB, et al. The ocular fundus findings in dengue fever. Gaoxiong Yi Xue Ke Xue Za Zhi 1989;5:24–30.
  10. National Vector Borne Disease Control Programme. Dengue Cases and Deaths in the Country Since 2008. Available at: (last accessed on November 4, 2012).
  11. Teoh SC, Chan DP, Nah GK, et al. A re-look at ocular complications in dengue fever and DHF. Dengue Bull 2006;30:184–193.
  12. Chhina DK, Goyal O, Goyal P, et al. Haemorrhagic manifestations of dengue fever and their manage-ment in a tertiary care hospital in north India. Indian J Med Res 2009;129:718–720.
  13. Chan DP, Teoh SC, Tan CS, et al. Ophthalmic complications of dengue. Emerg Infect Dis 2006;12:285–289. DOI: 10.3201/eid1202.050274.
  14. Sanjay S, Wagle AM, Au Eong KG. Optic neuropathy associated with dengue fever. Eye 2008;22:722–724. DOI: 10.1038/eye.2008.64.
  15. Kapoor HK, Bhai S, John M, et al. Ocular manifestations of dengue fever in an East Indian epidemic. Can J Ophthalmol 2006;41:741–746. DOI: 10.3129/i06-069.
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