Journal of Mahatma Gandhi University of Medical Sciences and Technology

Register      Login

VOLUME 6 , ISSUE 3 ( September-December, 2021 ) > List of Articles

CASE SERIES

Paget's Disease of Breast: One-year Experience of a Superspecialty Cancer Hospital

Aashish K Gupta, Neha Sethi, Maneesh K Vijay, Sangeeta Hudda, Chetna Mehrol, M L Yadav, Manju Raghava

Keywords : Infiltrating ductal carcinoma, Paget's disease, Pagetoid spread

Citation Information : Gupta AK, Sethi N, Vijay MK, Hudda S, Mehrol C, Yadav ML, Raghava M. Paget's Disease of Breast: One-year Experience of a Superspecialty Cancer Hospital. J Mahatma Gandhi Univ Med Sci Tech 2021; 6 (3):89-92.

DOI: 10.5005/jp-journals-10057-0187

License: CC BY-NC 4.0

Published Online: 29-03-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Paget's disease of the breast is an uncommon type of cancer of nipple-areola complex and it is frequently associated with an underlying in situ or invasive carcinoma. If there is persistent eczematous involvement of the nipple, which does not respond to the local treatment, then suspicion for Paget's disease must be considered. It constitutes 1–4.3% all breast cancer cases and is frequently associated with an underlying malignancy. Paget's disease of the nipple is a rare disease that requires high suspicion and a good knowledge of symptomatology for quick diagnosis. The present study is based on four cases of Paget's disease which were evaluated further to identify the underlying cause.


HTML PDF Share
  1. S. Dubar, Boukrid M., de Joliniere JB, et al., Paget's Breast Disease: A Case Report and Review of the Literature Front Surg 2017;4:51. Published online 2017. DOI: 10.3389/fsurg.2017.00051
  2. Karakas C. Paget's disease of the breast J Carcinog 2011;10:31. DOI: 10.4103/1477–3163.90676
  3. Challa VR, Deshmane V. Challenges in diagnosis and management of Paget's disease of the breast-a retrospective study. Indian J Surg 2015;77(Suppl 3):1083–1087. DOI: 10.1007/s12262-014-1167-6. Epub 2014. PMID: 27011515; PMCID: PMC4775644.
  4. Xie B, Zheng H, Lan H, et al. Synchronous bilateral Paget's disease of the breast: a case report. Oncol Lett 2012;4(1):83–85. DOI: 10.3892/ol.2012.676. Epub 2012. PMID: 22807966; PMCID: PMC3398373.
  5. Liu J, Zhao Z, Zhou J, et al. An unusual presentation of Paget's disease of the nipple in a young woman: a case report. Int J Clin Exp Med 2015;8(3):4694–4696. PMID: 26064405; PMCID: PMC4443239.
  6. Sun YS, Zhao Z, Yang ZN, et al. Risk factors and preventions of breast cancer. Int J Biol Sci 2017;13(11):1387–1397. Published 2017. DOI: 10.7150/ijbs.21635.
  7. Elenwo SN, Jamabo RS. Paget's disease of the breast: a case series. Int Surg J 2020;7(8):2706–2708. DOI: 10.18203/2349-2902.isj20203258
  8. Bellizzi. An algorithmic immunohistochemical approach to define tumor type and assign site of origin. Adv Anat Pathol 2020;27(3):114–163. DOI: 10.1097/PAP.0000000000000256
  9. Sharma GN, Dave R, Sanadya J, et al. Various types and management of breast cancer: an overview. J Adv Pharm Technol Res 2010;1(2): 109–126. PMID: 22247839; PMCID: PMC3255438.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.