Background and objectives: Hepatitis B and C are viral infections that can cause both acute and chronic liver diseases. These viruses are most commonly transmitted from mother to child during birth and delivery, as well as through contact with blood or other body fluids during sex with an infected partner, unsafe injections, or exposures to sharp instruments. However, it could be caused by nonintact skin or mucous membranes coming into touch with tears, saliva, or blood-carrying hepatitis B virus (HBV)—infected fluids or by sharing toothbrushes. Hepatitis C virus (HCV) is highly prevalent in slum areas of India. This study aimed to determine the prevalence of HBV and HCV infection in a slum area of Goner in Jaipur, India. Materials and methods: A total of 101 patients were enrolled in the study from October 2018 to April 2019 and tested for the presence of hepatitis B surface antigen (HBsAg) and anti-hepatitis C antibodies by enzyme-linked immunosorbent assay (ELISA) method. The study was conducted in slum areas, and the results were analyzed using descriptive statistics. Results: Among the 101 cases enrolled, 54 (53.46%) were males and 47 (46.53%) were females. The prevalence of HBV and HCV was found to be 2.97 and 0.99%, respectively. The most affected age-group was above 70 years of age and the 40–50 years age-group. Conclusion: The prevalence of HBV was found to be 2.97%, and only 0.99% for HCV. There is a need to carry out regular surveillance and test for other hepatitis-causing viruses, too.