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VOLUME 7 , ISSUE 2 ( May-August, 2022 ) > List of Articles


Association of Chest Computed Tomography Severity Score with Oxygen Requirement D-dimer CRP and Comorbidities in Patients with COVID-19 Infection

Mukesh K Sarna, Pradeep Agarwal, Manish R Pahadia, Sudha Sarna, Kishore Moolrajani, Shail D Upadhyaya, Surbhi Kapoor

Keywords : COVID-19, CT severity score, Hypoxia, SpO2, SARS-CoV-2

Citation Information : Sarna MK, Agarwal P, Pahadia MR, Sarna S, Moolrajani K, Upadhyaya SD, Kapoor S. Association of Chest Computed Tomography Severity Score with Oxygen Requirement D-dimer CRP and Comorbidities in Patients with COVID-19 Infection. J Mahatma Gandhi Univ Med Sci Tech 2022; 7 (2):39-43.

DOI: 10.5005/jp-journals-10057-0197

License: CC BY-NC 4.0

Published Online: 27-02-2023

Copyright Statement:  Copyright © 2022; The Author(s).


Objective: Chest CT has higher sensitivity in comparison to reverse transcription-polymerase chain reaction (RT-PCR) for COVID-19 diagnosis. We aim to identify the association of CT severity scores (CTSS) with lab markers and the need for oxygen. Methods: Cross-sectional observational study of 104 COVID-19 RT-PCR positive hospitalized patients. Patients underwent pulmonary CT, and their CTSS was calculated. SpO2, D-dimer and C-reactive protein (CRP) were also measured. The data was then collected and analyzed. Results: CT Severity Score (CTSS) was higher in patients above 50 years of age and males, though statistically insignificant. CTSS was positively correlated with D-dimer (p = 0.048) and oxygen requirement (0.000). However, HbA1C was lower in patients with higher CTSS. Conclusion: High CTSS correlates well with oxygen requirement, low SpO2, and high D-dimer but not with CRP and HbA1C. Our data suggest that CTSS can help predict disease outcomes by assessing disease severity.

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