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VOLUME 7 , ISSUE 1 ( January-April, 2022 ) > List of Articles
Hari Prasad Paliwal, Chakrapani Mittal, Anchin Kalia, Mukesh Jain, Shrikant Choudhary, Puneet Rijhwani, Sumeet Garg
Keywords : Dengue, Platelet count, Vitamin B12
Citation Information : Paliwal HP, Mittal C, Kalia A, Jain M, Choudhary S, Rijhwani P, Garg S. Correlation of Vitamin B12 Levels with Degree of Thrombocytopenia in Dengue Patients. J Mahatma Gandhi Univ Med Sci Tech 2022; 7 (1):1-3.
License: CC BY-NC 4.0
Published Online: 31-08-2022
Copyright Statement: Copyright © 2022; The Author(s).
Introduction: Dengue fever, commonly known as breakbone fever is the most common arboviral mosquito-borne disease in the world. Aims of the study was to find any correlation of vitamin B12 levels with the degree of thrombocytopenia in dengue patients. Materials and methods: A hospital-based study from January 2019 to June 2020 at the Department of General Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur. The study was done on dengue fever patients with severe thrombocytopenia (<50,000 μL and >2 days duration). Results: Mean platelet count in patients with ≤200 pg/mL vitamin B12 was 38,653.06 ± 6362.49 per mL and in patients with >200 pg/mL vitamin B12 was 40,564.35 ± 61.04.78 per mL. Mean platelet recovery in patients with ≤200 pg/mL vitamin B12 was 7.00 ± 1.04 days and in patients with >200 pg/mL vitamin B12 was 4.33 ± 0.59 days. Mean hospital stay in patients with ≤200 pg/mL vitamin B12 was 7.96 ± 0.71 days and in patients with >200 pg/mL, vitamin B12 was 4.49 ± 0.50 days. Conclusion: Vitamin B12 deficiency may be a contributing factor to the development of severe thrombocytopenia in dengue fever, particularly in the Indian population. Vitamin B12 deficiency may prolong the hospital stay and increase the platelet recovery time.