Journal of Mahatma Gandhi University of Medical Sciences and Technology

Register      Login

VOLUME 6 , ISSUE 3 ( September-December, 2021 ) > List of Articles


Unusual Presentation of Central Neurocytoma in Posterior Part of Third Ventricle Extending into Fourth Ventricle

Vishwajeet A Burungale, Anjaneya S Kathait, Hemant K Mishra, Ripudaman S Champawat

Keywords : Hydrocephalus, Central neurocytoma, Ventricular tumor

Citation Information : Burungale VA, Kathait AS, Mishra HK, Champawat RS. Unusual Presentation of Central Neurocytoma in Posterior Part of Third Ventricle Extending into Fourth Ventricle. J Mahatma Gandhi Univ Med Sci Tech 2021; 6 (3):93-96.

DOI: 10.5005/jp-journals-10057-0188

License: CC BY-NC 4.0

Published Online: 29-03-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Central neurocytomas (CNs) are usually located in the lateral ventricles. Primary origin in the third ventricle is very rare. We discuss the clinical signs and radiological findings of this tumor. We report a case of a third ventricle CN extending through a cerebral aqueduct in the fourth ventricle in a 40-year-old male patient, who initially presented with progressive headache, vertigo, and blurred vision for 3–4 months. Magnetic resonance imaging of the brain revealed a slightly enhanced tumor in the third ventricle with small necrotic areas, calcification, and obstructive hydrocephalus. Total surgical removal of the tumor was performed. The tumor was diagnosed as a CN on histopathological studies. CNs located in the third ventricle are rare. Total tumor excision is associated with a favorable prognosis.

  1. Hassoun J, Gambarelli D, Grisoli F, et al. Central neurocytoma: an electron–microscopic study of two cases. Acta Neuropathol 1982;56(2):151–156. DOI: 10.1007/BF00690587
  2. Hassoun J, Söylemezoglu F, Gambarelli D, et al. Central neurocytoma: a synopsis of clinical and histological features. Brain Pathol 1993;3(3):297–306. DOI: 10.1111/j.1750-3639.1993.tb00756.x
  3. Ishiuchi S, Tamura M. Central neurocytoma: An immunohistochemical, ultrastructural and cell culture study. Acta Neuropathol 1997;94(5):225–435. DOI: 10.1007/s004010050729
  4. Majos C, Coll S, Pons LC. Central neurocytoma arising within the ventricle. Neuroradiology 1997;39(4):270–272. DOI: 10.1007/s002340050406
  5. Takao H, Nakagawa K, Ohtomo K. Central neurocytoma with craniospinal dissemination. J Neurooncol 2003;61(3):255–259. DOI: 10.1023/a:1022553110232
  6. Buccoliero AM, Caldarella A, Ammannati F, et al. Extraventricular neurocytoma: morphological and immunohistochemistry considerations on medical diagnosis. Pathol Res Pract 2002;198(9): 627–633. DOI: 10.1078/0344-0338-00312
  7. Smith A, Smirniotopoulos J, Horkanyne-Szakaly I, et al. From the radiologic pathology archives: intraventricular neoplasms: radiologic-pathologic correlation. Radiographics 2013;33(1):21–43. DOI: 10.1148/rg.331125192.
  8. Drevelengas A, Polyzoides K, Kalaitzoglou I. Intraventricular neurocytoma: case report and review. Eur J Radiol 1994;19(1):14–18. DOI: 10.1016/0720-048X(94)00555-q
  9. Park S-H, Ostrzega N, Akers M-A, et al. Intraventricular neurocytoma with prominent myelin figures. Ultrastruct Pathol 1999;23(5):311–317. DOI: 10.1080/019131299281455
  10. Agranovich AL, Ang L-C, Fryer CJH. Central neurocytoma: report of 2 cases and literature review. J Neurooncol 1993;16(1):47–53. DOI: 10.1007/BF01324834
  11. Robbins P, Segal A, Narula S, et al. Central neurocytoma: a clinicopathological, immunohistochemical and ultrastructural study of seven cases. Pathol Res Pract 1995;191(2):100–111. DOI: 10.1016/S0344-0338(11)80559-5
  12. Warmuth-Metz M, Klein R, Sorensen N, et al. Central neurocytoma of the fourth ventricle. J Neurosurg 1999;91(3):506–509. DOI: 10.3171/jns.1999.91.3.0506
  13. Mackenzie IRA. Central neurocytoma: histologic atypia, proliferation, and clinical outcome. Cancer 1999;85(7):1606–1610. DOI: 10.1002/(sici)1097-0142(19990401)85:7<1606::aid-cncr24>;2-b
  14. Ng TH, Wong AY, Compton JS, et al. Pigmented central neurocytoma: case report and literature review. Am J Surg Pathol 1999;23(9):1136–1140. DOI: 10.1097/00000478-199909000-00019
  15. Soylemezoglu F, Scheithauer BW, Esteve J, et al. Atypical central neurocytoma. J Neuropathol Exp Neurol 1997;56(5):551–556. DOI: 10.1097/00005072-199705000-0001110.1097/00005072-199705000-00011
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.