Journal of Mahatma Gandhi University of Medical Sciences and Technology

Register      Login

VOLUME 5 , ISSUE 3 ( September-December, 2020 ) > List of Articles


A Rare Case of “Symptomatic Bilateral Adrenal Myelolipoma”

Niharika Jain, Parul Gautam, Abha Mathur, Mohan Lal Yadav

Citation Information : Jain N, Gautam P, Mathur A, Yadav ML. A Rare Case of “Symptomatic Bilateral Adrenal Myelolipoma”. J Mahatma Gandhi Univ Med Sci Tech 2020; 5 (3):100-102.

DOI: 10.5005/jp-journals-10057-0127

License: CC BY-NC 4.0

Published Online: 01-12-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Introduction: Adrenal myelolipoma is a benign neoplasm composed of mature adipose tissue and scattered islands of hematopoietic elements. Although the true incidence of these tumors is unknown, the incidence estimated to be is quite less. These lesions are usually unilateral and asymptomatic and are very rarely found as bilateral tumors. Aims and objectives: To present a rare case of “Symptomatic Bilateral Adrenal Myelolipoma”. Materials and methods: A 53-year-old woman presented with complaints of pain abdomen for 6 months. Physical examination was unremarkable. Computed tomography (CT) scan of the abdomen revealed a well-defined, round lesion bilaterally with heterogeneous attenuation suggesting the possibility of myelolipoma. The patient was subjected to bilateral adrenalectomy and the bilateral adrenal masses were sent for histopathological examination. Results: The histopathological evaluation of masses confirmed the diagnosis of bilateral adrenal myelolipoma. Conclusion: Although mostly discovered as an “incidentaloma”, the diagnosis of adrenal myelolipoma warrants through diagnostic study. Surgical resection is the mainstay as it prevents complications, such as spontaneous rupture and hemorrhage of the mass.

  1. Gierke E. Uber knochenmarksgwebe in der nebenniere. Zeiglers Beitr Path Anat 1905(Suppl. 7):311–324.
  2. Lam AKY, Chuah KL, de Pinieux G, et al. World Health Organization Classification of Tumours of Endocrine Organs. 4th ed., Lyon: IARC Press; 2017.
  3. Olsson CA, Krane RJ, Klugo RC, et al. Adrenal myelolipoma. Surgery 1973;73:665.
  4. McDonnell WV. Myelolipoma of adrenal. Arch Path 1956;61:416.
  5. Lack E, Wienke J. Diagnostic Histopathology of Tumors Fletcher CDM, ed., vol. 1 4th ed., Elsevier Saunders; 2013.
  6. Meyer A, Behrend M. Presentation and therapy of myelolipoma. Int J Urol 2005;12(no. 3):239–243. DOI: 10.1111/j.1442-2042.2005.01034.x.
  7. Dyckman J, Freedman D. Myelolipoma of the adrenal with clinical features and surgical excision. J Mt Sinai Hosp 1957;24:793.
  8. deBlois GG, DeMay RM. Adrenal myelolipoma diagnosis by computed-tomography-guided fine-needle aspiration. A case report. Cancer 1985;55(4):848. DOI: 10.1002/1097-0142(19850215)55:4<848::AID-CNCR2820550423>3.0.CO;2-2.
  9. Vierna J, Laforga JB. Giant adrenal myelolipoma. Scand J Urol Nephrol 1994;28(no. 3):301–304. DOI: 10.3109/00365599409181284.
  10. Boudreaux D, Waisman J, Skinner DG, et al. Giant adrenal myelolipoma and testicular interstitial cell tumor in a man with congenital 21-hydroxylase deficiency. Am J Surg Pathol 1979;3(2)):109–123. DOI: 10.1097/00000478-197904000-00002.
  11. Han M, Burnett AL, Fishman EK, et al. The natural history and treatment of adrenal myelolipoma. J Urol 1997;157(no. 4):1213–1216. DOI: 10.1016/S0022-5347(01)64926-7.
  12. Tyritzis SI, Adamakis I, Migdalis V, et al. Giant adrenal myelolipoma, a rare urological issue with increasing incidence: a case report. Cases J 2009;2(no. 9):8863. DOI: 10.4076/1757-1626-2-8863.
  13. Daneshmand S, Quek ML. Adrenal myelolipoma: Diagnosis and management. J Urol 2006;3:71–74.
  14. Kenney PJ, Wagner BJ, Rao P, et al. Myelolipoma: CT and pathologic features. Radiology 1998;208(no. 1):87–95. DOI: 10.1148/radiology.208.1.9646797.
  15. Répássy DL, Csata S, Sterlik G, et al. Giant adrenal myelolipoma. Pathol Oncol Res 2001;7(1):72–73. DOI: 10.1007/BF03032610.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.