Journal of Mahatma Gandhi University of Medical Sciences and Technology

Register      Login

VOLUME 3 , ISSUE 3 ( September-December, 2018 ) > List of Articles


Disseminated Histoplasmosis: A Rare Case Report

Meenu Roat, Jyotirmaya Gohli, Suresh Chandra Gupta

Keywords : Adrenal, Computed tomography, Disseminated histoplasmosis, Immunocompromised, Magnetic resonance imaging

Citation Information : Roat M, Gohli J, Gupta SC. Disseminated Histoplasmosis: A Rare Case Report. J Mahatma Gandhi Univ Med Sci Tech 2018; 3 (3):99-101.

DOI: 10.5005/jp-journals-10057-0085

License: CC BY-NC 4.0

Published Online: 01-06-2020

Copyright Statement:  Copyright © 2018; The Author(s).


Progressive disseminated histoplasmosis is a rare fungal infection and occurs in immunocompromised and immunosuppressed patients in the endemic area. It is difficult to differentiate it from tuberculosis on the basis of imaging finding alone. Here, we report a biopsy proven case of bilateral adrenal histoplasmosis with involvement of central nervous system (CNS). This patient showed good response to antifungal treatment.

PDF Share
  1. Grover S, Midha N, Gupta M, et al. Imaging spectrum in disseminated histoplasmosis: case report and brief review. Australas Radiol 2005;49(2):175–178. DOI: 10.1111/j.1440-1673.2005.01369.x.
  2. Kawashima A, Sandler CM, Fishman EK, et al. Spectrum of CT findings in nonmalignant disease of the adrenal gland. Radiographics 1998;18(2):393–412. DOI: 10.1148/radiographics.18.2.9536486.
  3. Gibb WRG, Ramsay AD, McNeil NI, et al. Bilateral adrenal masses. Br Med J (Clin Res Ed) 1985;291(6489):203–204. DOI: 10.1136/bmj.291.6489.203.
  4. Radin DR. Disseminated histoplasmosis: abdominal CT findings in 16 patients. AJR Am J Roentgenol 1991;157(5):955–958. DOI: 10.2214/ajr.157.5.1927816.
  5. Starkey J, Moritani T, Kirby P. MRI of CNS fungal infections: review of aspergillosis to histoplasmosis and everything in between. Clin Neuroradiol 2014;24(3):217–230. DOI: 10.1007/s00062-014- 0305-7.
  6. Saccente M, McDonnell RW, Baddour LM, et al. Cerebral histoplasmosis in the azole era: report of four cases and review. South Med J 2003;96(4):410–416. DOI: 10.1097/01.SMJ.0000051734.53654.D0.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.